Review
Year : 2025 | Volume : 9 | Issue : 1 | Page : 27-37
Dental pulp in health and disease - a review with notes on basic three-dimensional tissue organization
Sandhya Tamgadge 1*, Bhavani Nagendra. Sangala2, Bhagyashree P Agre3, Pratibha Kavale 2, Avinash Tamgadge 1
1 Dept of Oral & Maxillofacial Pathology and Microbiology, D.Y.Patil (Deemed to be university), School of Dentistry,
Nerul, Navi Mumbai, Maharashtra, India.
2 Dept of Oral & Maxillofacial Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental college and Hospital, Navi Mumbai, Maharashtra, India.
3 Dept of Public health dentistry Bharati Vidyapeeth ( Deemed to be University) dental college and hospital, Pune, India.
Address for correspondence:
Dept of Oral & Maxillofacial Pathology and Microbiology, D.Y.Patil (Deemed to be university), School of Dentistry, Nerul,
Navi Mumbai, Maharashtra, India.
E‐mail: sandhya.tamgadge@gmail.com
Abstract
In health, the dental pulp functions as a sensory organ, detecting external stimuli such as temperature, pressure, and chemical irritants. The pulp is also involved in dentinogenesis. This process helps maintain tooth integrity throughout an individual's lifetime. Furthermore, the dental pulp acts as a reservoir for stem cells, which have the potential to differentiate into various cell types, including odontoblasts and fibroblasts. This regenerative capacity is a cornerstone of dental pulp's role in health, aiding in the repair of minor injuries or damages to the tooth structure. Dental pulp can become vulnerable to various diseases and conditions, potentially leading to pain, infection, and tooth loss. Pulpitis, characterized by pulp inflammation, often results from untreated dental caries (cavities) or trauma. If left untreated, pulpitis can be irreversible, necessitating root canal therapy to remove the affected tissue. In severe cases, when infection breaches the pulp chamber, an abscess can form, posing significant health risks if not promptly addressed. Furthermore, systemic diseases, such as diabetes, can impact the pulp's vascularization and regenerative capabilities, affecting overall dental health. Dental professionals must understand the intricate relationship between dental pulp and health. Timely diagnosis and appropriate management of pulp-related conditions are crucial to preserving oral health and preventing systemic complications. This review also includes a note on the third dimension of the basic organization of dental pulp.
Acknowledgment
Nil
Conflict of interest
Nil
Source of funding
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How to cite this article: Tamgadge , S., Sangala, B., P Agre, B., Kavle, P., & Avinash. (2025). Dental pulp in health and disease -a review with notes on basic three-dimensional tissue organization: Pulp in health and disease. International Journal of Clinicopathological Correlation, 9(1), 27–37. https://doi.org/10.56501/intjclinicopatholcorrel.v9i1.1249.
