Original Research

Year : 2026 | Volume : 17 | Issue : 1 | Page : 72-82

Comparative Evaluation of the Effect of Lyophilised Platelet-rich Plasma and Micro Osteoperforation on the Rate of Orthodontic Tooth Movement in Class I Bimaxillary Protrusion Patients: A Split Mouth Study

Mohamed Shafi Nalla Mohamed 1, S.D. Milling Tania 2, Bevin Shaga 3, S. Veerasankar 3, A. Jebilla Pringle 4, Mary Sheloni Missier 4, C. Priyadharshini 4

1-Postgraduate Resident, 2-Professor, 3-Reader, 4-Senior Lecturer, Department of Orthodontics, Rajas Dental College and Hospital, Kavalkinaru, Tamil Nadu - 627105.

Address for Correspondence:

Mohamed Shafi Nalla Mohamed

Postgraduate Resident,

Department of Orthodontics

Rajas Dental College and Hospital, Kavalkinaru

Tamil Nadu - 627105.

ABSTRACT

BACKGROUND: Orthodontic tooth movement is often time-consuming and can cause patient discomfort. Various techniques to accelerate tooth movement such as micro-osteoperforation and platelet-rich plasma (PRP) have been extensively researched. PRP is an autologous component rich in growth factors and mediators that promote cell proliferation and differentiation, essential for orthodontic tooth movement. Freeze-drying PRP enhances its shelf life and clinical applicability.

AIM: The present study aims to evaluate the efficacy of lyophilised platelet-rich plasma (LPRP) and micro-osteoperforation (MOP) in accelerating canine retraction in patients with class I bimaxillary protrusion undergoing fixed orthodontic treatment.

MATERIALS AND METHODS: This randomized split-mouth clinical trial was conducted at the Department of Orthodontics and Dentofacial Orthopaedics, Rajas Dental College and Hospitals, Tirunelveli. Nine patients with Class I bimaxillary protrusion were randomly assigned to receive either MOP or LPRP on the contralateral side. Tooth movement was assessed at one- and two-months post-intervention using dental cast. Statistical analysis of the data was performed, with a p-value of < 0.05 considered statistically significant.

RESULTS: The mean age of the participants was 21.00 ± 1.94 years with a total of 9 participants with 4 males and 5 females. It can be observed that in both the groups, the rate of canine retraction at three different time interval was highly significant (p<0.001) but minimal differences was seen between LPRP and MOP groups which was not statistically significant.

CONCLUSION: This study demonstrated that both MOP and LPRP showed accelerated tooth movement over the course of two months ,while the difference  between the two groups was not statistically significant. Future studies to further validate these findings with larger sample sizes are recommended.
KEYWORDS: Malocclusion; Orthodontics; Micro-osteoperforation; Platelet-rich plasma; Regional acceleratory phenomenon.

CONFLICT OF INTEREST AND FUNDING

Nil

How to cite this article: Mohamed Shafi Nalla Mohamed, S.D. Milling Tania, Bevin Shaga, S. Veerasankar, A. Jebilla Pringle, Mary Sheloni Missier, C. Priyadharshini. Comparative Evaluation of the Effect of Lyophilised Platelet-rich Plasma and Micro-Osteoperforation on the Rate of Orthodontic Tooth Movement in Class I Bimaxillary Protrusion Patients: A Split Mouth Study.

Int J Orthod Rehabil 2026; 17 (1): 72-82.

Doi: 10.56501/Intjorthodrehabil.171.ijor0054

Original Research

Year : 2025 | Volume : 16 | Issue : 4 | Page : 39-51

Comparison of Efficacy and Rate of Alignment using Three Different Arch wires: A Randomized Clinical Trial

 B Edward Giftson Noah1, S.D. Milling Tania2, S. Veerasankar3, Bevin Shaga3, Jebilla Pringle4, Razick Nishadh M4, Shahina Juneith4

 1Postgraduate Resident, 2Professor, 3Associate Professor, 4Assistant Professor, Department of Orthodontics, Rajas Dental College, Rajas Dental College And Hospital, Thirurajapuram, Kavalkinaru Jn, Tirunelveli - 627 105

Address for Correspondence:

Dr. S.D. Milling Tania,

Professor and HOD,
Rajas Dental College And Hospital

Thirurajapuram, Kavalkinaru Jn, Tirunelveli - 627 105
Email ID - drtania_d@yahoo.co.in

ABSTRACT

Aim: To compare the rate and efficiency of Niobium-Titanium-Tantalum Zirconium archwire (Gummetal), Copper Nickel Titanium archwire (CuNiTi) and conventional nickel titanium archwire (NiTi) on initial alignment.

Materials And Methods: A single-center randomized controlled clinical trial was conducted in 33 fully erupted dentition patients and Little’s Irregularity Index (LII) >2 mm. Patients were randomly assigned to three groups (n=11 each) treated with 0.014-inch NiTi, CuNiTi, or Gummetal archwires. Impressions were taken at baseline (T0) and at 3-week intervals for 4 times (T1–T4). LII, Intercanine width (ICW) and intermolar width (IMW) were measured and analyzed using SPSS v20.0 with Repeated Measures ANOVA, Bonferroni post-hoc, and Chi-square tests with p value <0.05 as statistical significance.

Results: All groups showed statistically significant reduction in LII from T0 to T4 (p<0.001). Group 1 showed a decrease from 3.76±0.75 to 1.02±0.53, Group 2 from 3.74±0.64 to 0.90±0.25, and Group 3 from 3.04±0.59 to 1.33±0.66. ICW increased significantly in all groups: Group 1 from 25.93±2.86 to 26.58±2.78 (p<0.001), Group 2 from 25.59±2.68 to 26.64±2.76 (p < 0.001), and Group 3 from 25.79±2.86 to 26.52±2.83 (p=0.008). IMW changes were significant in Group 2 (40.76±2.66 to 41.11±2.63, p<0.001) and Group 3 (40.95±2.61 to 41.11±2.63, p<0.001), but not in Group 1 (41.01±2.64 to 41.08±2.62, p=0.136). Intergroup comparison revealed no statistically significant difference in LII, ICW, or IMW (p≥0.051).

Conclusions: CuNiTi and NiTi archwires were more effective in initial alignment and mild arch expansion than Gummetal, making them preferable for early orthodontic correction.

Keywords: Archwires, Copper NiTi, Gummetal, Intercanine arch width

CONFLICT OF INTEREST

The authors have no conflict of interests to declare.

FUNDING

Nil.
How to cite this article: B Edward Giftson Noah, S.D. Milling Tania, S. Veerasankar, Bevin Shaga, Jebilla Pringle, Razick Nishadh M, Shahina Juneith.Comparison of Efficacy and Rate of Alignment using Three Different Arch wires: A Randomized Clinical Trial. Int J Orthod Rehabil 2025; 16 (4): 39-51.

Original Research

Year : 2023 | Volume : 14 | Issue : 1 | Page : 44-54

Comparative Evaluation of Antibacterial Activity of Chlorhexidine, Povidone Iodine and Glutaraldehyde for Disinfection of Orthodontic Appliances - An In-Vitro Study

Mary Violet Jeyapriya1 , S.D.Milling Tania2 , Sonali Rathore3 , Sheloni Missier4 , Bevin Shaga5

1Post Graduate, 2 Professor and Head of Department, 3Reader, 4,5Senior Lecturer, Department of Orthodontics, Rajas Dental College and Hospital, Kavalkinaru.

Address for Correspondence:

Mary Violet Jeyapriya ,

Post Graduate, Department of Orthodontics and Dentofacial Orthopaedics Rajas Dental College and Hospital, Kavalkinaru.

Email id: maryjeyapriya769@gmail.com

Contact number- 9941490302

ABSTRACT:

Introduction:

Orthodontists must take precautionary measures to protect patients from cross-infection as most materials supplied by manufacturers are not sterile.

Materials and methods :

A sample of 108 as received brackets, molar tubes and archwires equally divided in four groups (3 experimental groups, Group 1- Chlorhexidine Gluconate, Group 2 – Povidone Iodine, Group 3 - Glutaraldehyde and one Control (group 4) were used in this study. Three samples of each (brackets, archwires, molar bands) were tested for CFUs of each micro-organism (Staphylococcus aureus, Streptococcus mutans, and Lactobacillus acidophilus) in each group. The samples were incubated and spread on blood agar and the colony forming units (CFUs/ml) enumeration were done before and after disinfection.

Results:

Brackets and molar bands had least CFU/ml of Staphylococcus aureus after disinfection in Group 3 (p=0.000). Of allthe materials contaminated by Streptococcus mutans (p= 0.000) andLactobacillus acidophilus, the mean CFUs/ml were least in Group 2 ( p<0.05).

Conclusion:

2% Glutaraldehyde was effective against Staphylococcus aureus. 5% Povidone iodine was effective against Streptococcus mutans and Lactobacillus acidophilus. The antimicrobial activity of 5% Povidone Iodine was most effective followed by glutaraldehyde when compared to chlorhexidine gluconate. Keywords: Glutaraldehyde, Povidone Iodine, Chlorhexidine Gluconate, Disinfection, Orthodontic materials.

Keywords: Glutaraldehyde, Povidone Iodine, Chlorhexidine Gluconate, Disinfection, Orthodontic materials.

SOURCE OF FUNDING

Nil

CONFLICT OF INTEREST

The authors have no conflict of interest to declare.

How to cite this article: Mary Violet Jeyapriya, S.D.Milling Tania, Sonali Rathore, Sheloni Missier, & Bevin Shaga. (2023). A Comparative Evaluation of Antibacterial Activity of Chlorhexidine, Povidone Iodine and Glutaraldehyde for Disinfection of Orthodontic Appliances - An In-Vitro Study: Original Research. International Journal of Orthodontic Rehabilitation, 14(1), 44–54. https://doi.org/10.56501/intjorthodrehabil.v14i1.675